In recent years, much progress has been achieved in realizing highly controlled and coherent many-body systems. Examples of such systems include systems of ultra-cold atoms, molecules, systems of NV-centers in diamond, and superconductiong quibits. These remarkable experimental advances pose a conceptually new set of theoretical questions regarding the universal laws describing the evolution and relaxation of closed many-body systems. This workshop will cover the most exciting recent theoretical developments in the non-equilibrium many-body physics. Focus topics include thermalization in integrable and non-integrable strongly interacting systems, thermalization breakdown, periodically driven systems, and many-body localization in systems with quenched disorder. We will discuss key changes in the field and identify the possible routes to their solution.